Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056686 | 0.97 | MAPK1 (0.48) | MAPK1LMNACYP2C9GSK3AGSK3B | |
| Ammonia Solution, Strong SCHEMBL7267571 | 0.93 | MAPK1 (0.52) | MAPK1LMNACYP2C9CHRM2CHRM4 | |
| SCHEMBL20662427 | 0.93 | MAPK1 (0.46) | MAPK1LMNACYP2C9GSK3AGSK3B | |
| SCHEMBL44882 | 0.90 | — | — | |
| SCHEMBL278483 | 0.90 | MAPK1 (0.55) | MAPK1LMNACYP2C9GSK3AGSK3B | |
| SCHEMBL14434380 | 0.90 | — | — | |
| SCHEMBL44881 | 0.90 | — | — | |
| SCHEMBL22311884 | 0.90 | — | — | |
| SCHEMBL12955575 | 0.90 | — | — | |
| SCHEMBL18488229 | 0.90 | MAPK1 (0.48) | MAPK1LMNACYP2C9GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118109-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008112473-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |