Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22311884 | 0.97 | — | — | |
| SCHEMBL44881 | 0.97 | — | — | |
| SCHEMBL44882 | 0.97 | — | — | |
| SCHEMBL14434380 | 0.97 | — | — | |
| SCHEMBL12955575 | 0.97 | — | — | |
| Charcoal, Activated SCHEMBL11101400 | 0.93 | MAPK1 (0.52) | MAPK1LMNACYP2C9CHRM4CHRNB4 | |
| SCHEMBL1848113 | 0.93 | MAPK1 (0.52) | MAPK1LMNACYP2C9CHRM4CHRNB4 | |
| Iodide SCHEMBL5266075 | 0.93 | MAPK1 (0.52) | MAPK1LMNACYP2C9CHRM4CHRNB4 | |
| Hydrochloric Acid SCHEMBL16245107 | 0.93 | MAPK1 (0.52) | MAPK1LMNACYP2C9CHRM4CHRNB4 | |
| Ammonia Solution, Strong SCHEMBL4433798 | 0.93 | MAPK1 (0.46) | MAPK1LMNACYP2C9CHRM4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804051-A | Preparation method of granisetron intermediate | 杭州励德生物科技有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-102234231-B | 1-substituted-2-substituted-4- aryl substituted-butyl-2-alkene 1, 4-diketone compound, its preparation method and application | SHANGHAI INST MATERIA MEDICA | 2015-01-07 | — | — | CN | claimed |
| CN-102234231-A | 1-substituted-2-substituted-4- aryl substituted-butyl-2-alkene 1, 4-diketone compound, its preparation method and application | SHANGHAI INST MATERIA MEDICA | 2011-11-09 | — | — | CN | claimed |
| CN-1190436-C | Process for preparing granisetron and its salt | HAIZHENG PHARMACEUTICAL CO LTD (CN) | 2005-02-23 | — | — | CN | claimed |
| CN-1451660-A | Process for preparing granisetron and its salt | HAIZHENG PHARMACEUTICAL CO LTD (CN) | 2003-10-29 | — | — | CN | claimed |
| EP-0195498-A2 | Tropane derivatives, their synthesis and their use | MOBIL OIL CORPORATION (US) | 1986-09-24 | — | — | EP | claimed |
| CN-113855632-A | Benzcycloquine bromide nasal spray and preparation method thereof | 北京万全德众医药生物技术有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-110804051-B | Preparation method of granisetron intermediate | 杭州励德生物科技有限公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-110804051-A | Preparation method of granisetron intermediate | 杭州励德生物科技有限公司 | 2020-02-18 | — | — | CN | disclosed |
| CN-102234231-B | 1-substituted-2-substituted-4- aryl substituted-butyl-2-alkene 1, 4-diketone compound, its preparation method and application | SHANGHAI INST MATERIA MEDICA | 2015-01-07 | — | — | CN | disclosed |
| CN-103159754-A | Amino propyl substituted tropane amine compound, pharmaceutical composition thereof, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-06-19 | — | — | CN | disclosed |
| CN-101585835-B | Preparation method and application of bencycloquidium bromide optical isomer and composition of bencycloquidium bromide optical isomer | BEIJING JIASHILIANBO PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-08-22 | — | — | CN | disclosed |
| CN-102234231-A | 1-substituted-2-substituted-4- aryl substituted-butyl-2-alkene 1, 4-diketone compound, its preparation method and application | SHANGHAI INST MATERIA MEDICA | 2011-11-09 | — | — | CN | disclosed |
| CN-1451660-A | Process for preparing granisetron and its salt | HAIZHENG PHARMACEUTICAL CO LTD (CN) | 2003-10-29 | — | — | CN | disclosed |
| EP-0315390-B1 | Novel 4-oxobenzotriazines and 4-oxoquinazolines | BEECHAM GROUP PLC (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-4959367-A | ANALGESICS, TRANQUILIZERS, GASTROINTESTINAL, CNS | BEECHAM GROUP P.L.C. (GB) | 1990-09-25 | — | — | US | disclosed |
| EP-0315390-A2 | Novel 4-oxobenzotriazines and 4-oxoquinazolines | BEECHAM GROUP PLC (GB) | 1989-05-10 | — | — | EP | disclosed |
| EP-0195498-A3 | TROPANE DERIVATIVES, THEIR SYNTHESIS AND THEIR USE | MOBIL OIL CORPORATION (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0195498-A2 | Tropane derivatives, their synthesis and their use | MOBIL OIL CORPORATION (US) | 1986-09-24 | — | — | EP | disclosed |
| EP-0195498-A2 | Tropane derivatives, their synthesis and their use | MOBIL OIL CORPORATION (US) | 1986-09-24 | — | — | EP | disclosed |