Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.71 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362068 | 0.94 | — | — | |
| SCHEMBL10472630 | 0.87 | FAAH (0.69) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL1037246 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL7934446 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL1037235 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL4283094 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL7453244 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL2431478 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL6783832 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 | |
| SCHEMBL28679834 | 0.85 | FAAH (0.72) | ALDH1A1TRPA1FAAHNAAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121600-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | Boehringer Ingelheim International GmbH (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099000-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-21 | — | — | WO | disclosed |