Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305980 | 0.99 | CA12 (0.36) | TLR2PRCPCA12CA1CA2 | |
| SCHEMBL3403308 | 0.99 | CA12 (0.36) | TLR2PRCPCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4430625 | 0.97 | CA12 (0.36) | TLR2PRCPCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3308857 | 0.97 | CA12 (0.36) | TLR2PRCPCA12CA1CA2 | |
| SCHEMBL3307245 | 0.96 | PRCP (0.34) | TLR2PRCPCA12CA1CA2 | |
| SCHEMBL4430690 | 0.96 | PRCP (0.34) | TLR2PRCPCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4430687 | 0.94 | TLR2 (0.33) | TLR2PRCPCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3300548 | 0.94 | TLR2 (0.33) | TLR2PRCPCA12CA1CA2 | |
| Maleic Acid SCHEMBL6380880 | 0.91 | CA12 (0.33) | TLR2PRCPCA12CA1CA2 | |
| Fumaric Acid SCHEMBL6380885 | 0.91 | CA12 (0.33) | TLR2PRCPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125695-A2 | NITRIC OXIDE DONOR COMPOUNDS | Nicox S.A. (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |