Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307245 | 1.00 | PRCP (0.34) | PRCPCA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL3300548 | 0.99 | TLR2 (0.33) | PRCPCA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4430687 | 0.99 | TLR2 (0.33) | PRCPCA12CA1CA2CA4 | |
| SCHEMBL3403308 | 0.97 | CA12 (0.36) | PRCPCA12CA1CA2CA4 | |
| SCHEMBL3305980 | 0.97 | CA12 (0.36) | PRCPCA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL4430625 | 0.96 | CA12 (0.36) | PRCPCA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL3308857 | 0.96 | CA12 (0.36) | PRCPCA12CA1CA2CA4 | |
| SCHEMBL4433830 | 0.96 | TLR2 (0.36) | PRCPCA12CA1CA2CA4 | |
| Fumaric Acid SCHEMBL6373847 | 0.92 | MEN1 (0.33) | PRCPCA12CA1CA2CA4 | |
| Maleic Acid SCHEMBL6373843 | 0.92 | MEN1 (0.33) | PRCPCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635816-B1 | ENALAPRIL-NITROXYDERIVATIVES DERIVATIVES AND RELATED COMPOUNDS AS ACE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | NICOX SA (FR) | 2009-03-04 | — | — | EP | disclosed |
| US-7217733-B2 | ACE inhibitor derivatives | NICOX, S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| CN-1809345-A | Enalapril-nitroxyderivatives derivatives and related compounds as ACE inhibitors for the treatment of cardiovascular diseases | NICOX SA (FR) | 2006-07-26 | — | — | CN | disclosed |
| EP-1635816-A1 | ENALAPRIL-NITROXYDERIVATIVES DERIVATIVES AND RELATED COMPOUNDS AS ACE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | Nicox S.A. (FR) | 2006-03-22 | — | — | EP | disclosed |
| US-20050004100-A1 | ACE inhibitor derivatives | NICOX S.A. (FR) | 2005-01-06 | — | — | US | disclosed |
| WO-2004110432-A1 | ENALAPRIL-NITROXYDERIVATIVES DERIVATIVES AND RELATED COMPOUNDS AS ACE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | NICOX S.A. (FR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004100-A1 | ACE inhibitor derivatives | ACE, ACE2, AGTR1 | PRCP 1469/4885CA12 3057/4885CA1 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.