Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.66 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424571 | 1.00 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9007734 | 0.91 | THRB (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23636 | 0.89 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28149678 | 0.89 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| Tetradecane SCHEMBL21989973 | 0.88 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5884750 | 0.87 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Propane SCHEMBL28078056 | 0.87 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28120744 | 0.87 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10391726 | 0.87 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12310182 | 0.86 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4624971-A | Photo setting composition for coating substrates with an abrasion-resistant transparent or translucent film | BATTELLE DEVELOPMENT CORPORATION (US) | 1986-11-25 | — | — | US | claimed |
| US-7514502-B2 | Thermoplastic resin composition having improved external appearance and excellent weatherability | LG CHEM, LTD. (KR) | 2009-04-07 | — | — | US | disclosed |
| EP-1631621-B1 | THERMOPLASTIC RESIN COMPOSITION HAVING IMPROVED EXTERNAL APPEARANCE AND EXCELLENT WEATHERABILITY | LG CHEMICAL LTD (KR) | 2009-03-11 | — | — | EP | disclosed |
| US-20060148992-A1 | Thermoplastic resin composition having improved external appearance and excellent weatherability | LG CHEM, LTD. (KR) | 2006-07-06 | — | — | US | disclosed |
| EP-0630641-B1 | Method and dispenser for making dental products | DENTSPLY INT INC (US) | 2000-10-11 | — | — | EP | disclosed |
| US-5554665-A | PHOTO OR THERMAL ACRYLIC POLYMERIZATION | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0630641-A1 | Method and dispenser for making dental products | DENTSPLY INTERNATIONAL, INC. (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5210109-A | Dentistry, addition-polymerizable and crosslinkable rubber-modified polymer | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0427300-A1 | Interpenetrating polymer network compositions | DENTSPLY INTERNATIONAL, INC. (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4863977-A | Process for preparing interpenetrating polymer network objects employing rubber-modified polymers | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4857493-A | Polymer latexes containing metal ions and complexes | FORD WARREN T (US) | 1989-08-15 | — | — | US | disclosed |
| US-4711913-A | CROSSLINKED ADDITION POLYMER BLENDS; DENTURES | DENTSPLY INTERNATIONAL INC. (US) | 1987-12-08 | — | — | US | disclosed |
| US-4595716-A | Resinous reaction product comprising mixture of addition polymerized monomer, aromatic epoxy resin, extender polymer, graft polymers of each of the epoxy resin and the extender polymer | SCM CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |
| US-4551486-A | DENTISTRY | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1985-11-05 | — | — | US | disclosed |
| EP-0142747-A2 | Interpenetrating polymer network compositions employing rubber-modified polymers | DENTSPLY INTERNATIONAL, INC. (US) | 1985-05-29 | — | — | EP | disclosed |
| US-4482671-A | Base for a graft polymer, novel graft polymer compositions, solvent and water-reducible coatings incorporating the novel graft polymers, and processes for making them | SCM CORPORATION (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0041108-A2 | Base for a graft polymer, novel graft polymer compositions, solvent and water-reducible coatings incorporating the novel polymers, and processes for making them | SCM CORPORATION (US) | 1981-12-09 | — | — | EP | disclosed |