SCHEMBL4434997

SCHEMBL4434997

ClCCCCCCCCCCC(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16969909 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL16969668 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL16969779 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL16970227 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL2561520 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL16969621 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL11370229 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL16970062 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL5505037 1.00 TSHR (0.40) TSHRALDH1A1TDP1
SCHEMBL16970112 1.00 TSHR (0.40) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115125629-A Textile fiber material with heat storage and temperature adjustment functions and preparation method thereof 江苏领智健康科技有限公司 2022-09-30 CN claimed
CN-114106443-A Antibacterial heat-shrinkable tube and preparation method and application thereof 上海长园电子材料有限公司 2022-03-01 CN claimed
CN-108822550-B Preparation method of novel liquid crystal elastomer material 浙江鑫都文化用品股份有限公司 2021-06-04 CN claimed
CN-115125629-B Textile fiber material with heat storage and temperature regulation functions and preparation method thereof 江苏领智健康科技有限公司 2022-12-02 CN disclosed
CN-115304789-A Double-bond-rich nanofiber gel prepared by chemical vapor deposition method and preparation method and application thereof 南京林业大学 2022-11-08 CN disclosed
CN-115260532-A Cellulose nanofiber hydrogel with mechanical color change and application thereof 南京林业大学 2022-11-01 CN disclosed
CN-115125629-A Textile fiber material with heat storage and temperature adjustment functions and preparation method thereof 江苏领智健康科技有限公司 2022-09-30 CN disclosed
CN-114106443-A Antibacterial heat-shrinkable tube and preparation method and application thereof 上海长园电子材料有限公司 2022-03-01 CN disclosed
CN-110857336-B Polymerizable lignin-based macromolecular photoinitiator and preparation method and application thereof 中国科学院理化技术研究所 2021-10-22 CN disclosed
CN-107365359-B Synthesis method of vancomycin chiral functional monomer 昆明理工大学 2021-06-04 CN disclosed
CN-107460186-B Silicone rubber immobilized chymotrypsin material and preparation method and application thereof 东南大学 2021-01-05 CN disclosed
US-20140072900-A1 Metal Ionophores in PEM Membranes GM Global Technology Operations LLC (US) 2014-03-13 US disclosed
US-20130071742-A1 LITHIUM ION BATTERIES GM Global Technology Operations LLC (US) 2013-03-21 US disclosed
EP-2125911-B1 SURFACE-BOUND FLUORINATED ESTERS FOR AMINE CAPTURE 3M INNOVATIVE PROPERTIES CO (US) 2013-01-23 EP disclosed
EP-2125911-A2 SURFACE-BOUND FLUORINATED ESTERS FOR AMINE CAPTURE 3M Innovative Properties Company (US) 2009-12-02 EP disclosed
WO-2008140599-A2 SURFACE-BOUND FLUORINATED ESTERS FOR AMINE CAPTURE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-11-20 WO disclosed
US-20080227169-A1 Immobilization 3M INNOVATIVE PROPERTIES COMPANY 2008-09-18 US disclosed
CN-1664014-A Thermochromatic materials containing unsaturated carbon chains and process for preparing same UNIV NORTHEASTERN (CN) 2005-09-07 CN disclosed
US-5451483-A Polyalkylene thermoplastic resin particles, liquids, pigments, adjuvants and charge directors for duvelopment XEROX CORPORATION (US) 1995-09-19 US disclosed
US-5166026-A Copolymer resin of eicosene with styrene and olefin and pigments XEROX CORPORATION (US) 1992-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227169-A1 Immobilization DAO, DNPEP, MSN TSHR 3444/4885ALDH1A1 1596/4885TDP1 3176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.