Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445474 | 0.88 | HCAR2 (0.48) | HCAR2 | |
| SCHEMBL441834 | 0.88 | HCAR2 (0.48) | HCAR2 | |
| SCHEMBL445009 | 0.88 | HCAR2 (0.48) | HCAR2 | |
| SCHEMBL7502212 | 0.82 | HCAR2 (0.57) | HCAR2ATMPLA2G1BATG4BTHRA | |
| SCHEMBL7502219 | 0.82 | HCAR2 (0.57) | HCAR2ATMPLA2G1BATG4BTHRA | |
| SCHEMBL29041003 | 0.81 | HCAR2 (0.56) | HCAR2ATMPLA2G1BATG4BTHRA | |
| SCHEMBL10673266 | 0.78 | HCAR2 (0.53) | HCAR2ATMPLA2G1BATG4BTHRA | |
| SCHEMBL1301122 | 0.78 | HCAR2 (0.53) | HCAR2ATMPLA2G1BATG4BTHRA | |
| SCHEMBL128174 | 0.78 | HCAR2 (0.53) | HCAR2ATMPLA2G1BATG4BTHRA | |
| SCHEMBL128175 | 0.78 | HCAR2 (0.53) | HCAR2ATMPLA2G1BATG4BTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |