Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445009 | 1.00 | HCAR2 (0.48) | HCAR2ACE2GPR84CA1FFAR1 | |
| SCHEMBL441834 | 1.00 | HCAR2 (0.48) | HCAR2ACE2GPR84CA1FFAR1 | |
| SCHEMBL443503 | 0.88 | HCAR2 (0.53) | HCAR2 | |
| SCHEMBL7502212 | 0.77 | HCAR2 (0.57) | HCAR2 | |
| SCHEMBL7502219 | 0.77 | HCAR2 (0.57) | HCAR2 | |
| SCHEMBL29041003 | 0.76 | HCAR2 (0.56) | HCAR2 | |
| SCHEMBL5023277 | 0.75 | FFAR4 (0.50) | GPR84FFAR1MAPTPPARD | |
| SCHEMBL295424 | 0.75 | FFAR4 (0.50) | GPR84FFAR1MAPTPPARD | |
| SCHEMBL11658389 | 0.75 | GPR84 (0.42) | ACE2GPR84CA1FFAR1MAPT | |
| SCHEMBL11658162 | 0.74 | GPR84 (0.46) | ACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |