Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F11 | P03951 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435115 | 0.89 | F10 (0.42) | F10F2F11LMNAMAPK1 | |
| SCHEMBL4435125 | 0.87 | F10 (0.41) | F10F2F11 | |
| SCHEMBL3448759 | 0.85 | F10 (0.51) | F10F2F11 | |
| SCHEMBL4441725 | 0.85 | F10 (0.41) | F10F2F11 | |
| SCHEMBL4582592 | 0.81 | F10 (0.42) | F10F2LMNAMAPK1KMT2A | |
| SCHEMBL3303858 | 0.79 | F10 (0.50) | F10F2F11 | |
| SCHEMBL3303853 | 0.79 | F10 (0.50) | F10F2F11 | |
| SCHEMBL3449536 | 0.75 | F10 (0.54) | F10F2F11KMT2A | |
| SCHEMBL4592037 | 0.74 | F10 (0.51) | F10F2F11 | |
| SCHEMBL3447270 | 0.74 | F10 (0.51) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2132193-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | Boehringer Ingelheim International GmbH (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |