Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3449130 | 0.83 | USP30 (0.55) | F10MAPK1RAB9AHTTUSP30 | |
| SCHEMBL3449128 | 0.83 | USP30 (0.55) | F10MAPK1RAB9AHTTUSP30 | |
| SCHEMBL4435200 | 0.81 | F10 (0.44) | F10KMT2AMAPK1LMNAF2 | |
| SCHEMBL4435115 | 0.81 | F10 (0.42) | F10KMT2AMAPK1LMNAF2 | |
| SCHEMBL8290168 | 0.79 | USP30 (0.57) | F10KMT2ARAB9AMEN1GAA | |
| SCHEMBL4435125 | 0.78 | F10 (0.41) | F10F2 | |
| SCHEMBL4436565 | 0.78 | F10 (0.42) | F10KMT2AMAPK1LMNARAB9A | |
| SCHEMBL4442146 | 0.77 | F10 (0.38) | F10KMT2AMAPK1LMNARAB9A | |
| SCHEMBL4436005 | 0.76 | F10 (0.40) | F10KMT2AMAPK1LMNARAB9A | |
| SCHEMBL4438714 | 0.75 | F10 (0.43) | F10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |