SCHEMBL4435322

SCHEMBL4435322

CC(CC(CC(C)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.57
ESR2 Q92731 7/20 0.57
PDCD1 Q15116 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
MIF P14174 1/20 0.48
CYP2C9 P11712 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CHRM2 P08172 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CHRM1 P11229 1/20 0.46
ALOX15 P16050 1/20 0.46
DRD1 P21728 1/20 0.46
TBXA2R P21731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865915 0.90 ESR1 (0.55) ESR1ESR2PDCD1CD274MIF
SCHEMBL16200780 0.90 ESR1 (0.55) ESR1ESR2PDCD1CD274MIF
SCHEMBL16200769 0.90 ESR1 (0.55) ESR1ESR2PDCD1CD274MIF
SCHEMBL13294722 0.90 ESR1 (0.55) ESR1ESR2PDCD1CD274MIF
SCHEMBL16200764 0.90 ESR1 (0.55) ESR1ESR2PDCD1CD274MIF
SCHEMBL12384051 0.90 ESR1 (0.58) ESR1ESR2PDCD1CD274MIF
SCHEMBL5607941 0.89 ESR1 (0.47) ESR1ESR2PDCD1CD274MIF
SCHEMBL6341136 0.88 ESR1 (0.64) ESR1ESR2PDCD1CD274MIF
SCHEMBL29833332 0.86 ESR1 (0.61) ESR1ESR2PDCD1CD274MIF
SCHEMBL7050045 0.86 ESR1 (0.44) ESR1ESR2PDCD1CD274MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105722656-B Pass through the method for frothing injection manufacture mechanograph, the mechanograph made of the thermoplastic to foam and application thereof 科思创德国股份有限公司 2019-06-25 CN disclosed
EP-2097478-A1 FILLED POLYCARBONATE COMPOSITIONS WITH MODIFIED RESILIENCE Bayer MaterialScience AG (DE) 2009-09-09 EP disclosed
WO-2008061644-A1 FILLED POLYCARBONATE COMPOSITIONS WITH MODIFIED RESILIENCE BAYER MATERIALSCIENCE AG (DE) 2008-05-29 WO disclosed
EP-0023650-B2 Use of alkaline and earth-alkaline salts of alkyl-substituted aromatic sulphonic acids, phosphonic acids and acid esters of phosphoric acid as internal antistatic agents for films of polycarbonate BAYER AG (DE) 1990-08-16 EP disclosed
EP-0183107-B1 FLAME RETARDANT MOLDING COMPOSITIONS MOBAY CORPORATION (US) 1989-03-29 EP disclosed
EP-0122759-B1 POLYCARBONATE COMPOSITIONS AND USE THEREOF HENKEL CORPORATION (a Delaware corp.) (US) 1989-01-11 EP disclosed
EP-0080767-B1 POLYMER COMPOSITION STAMICARBON B.V. (NL) 1986-08-13 EP disclosed
EP-0088947-B1 POLYCARBONATE-CALCITE COMPOSITIONS AND THEIR USE TO PREPARE FILMS MOBAY CORPORATION (US) 1986-05-14 EP disclosed
EP-0036080-B1 AROMATIC POLYESTER CARBONATES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF MOULDINGS, FILMS AND COATINGS BAYER AG (DE) 1984-11-28 EP disclosed
EP-0000060-B1 PROCESS FOR THE PREPARATION OF BIS-CARBONATES FROM DIPHENOLS AND POLYOXYALKYLENE GLYCOLS LENGTHENED BY CARBONATE GROUPS AND THEIR APPLICATION IN THE PREPARATION OF MACROMOLECULAR THERMOPLASTIC POLYCARBONATE POLYETHER BLOCK COPOLYMERS. BAYER AG (DE) 1980-08-06 EP disclosed