SCHEMBL443535

SCHEMBL443535

CCCCCCC(=O)NCC(C)C

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.64
MEN1 O00255 1/20 0.60
MAPK1 P28482 1/20 0.60
KMT2A Q03164 1/20 0.60
EPHX1 P07099 1/20 0.59
ASAH1 Q13510 1/20 0.55
HSP90AA1 P07900 1/20 0.55
DNM1 Q05193 2/20 0.53
CASP2 P42575 1/20 0.52
HPGD P15428 1/20 0.51
PSMB5 P28074 1/20 0.50
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
PLA2G10 O15496 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26491481 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL20876854 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL1457445 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL8372916 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
Tetrahydropellitorine SCHEMBL4878046 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL20883256 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL7432688 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL1456461 1.00 FAAH (0.64) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL9462479 0.98 FAAH (0.61) FAAHMEN1MAPK1KMT2AEPHX1
Hydrochloric Acid SCHEMBL5396087 0.96 FAAH (0.59) FAAHMEN1MAPK1KMT2AEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3691645-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING DELAYED RELEASE GELLING AGENT COMPOSITIONS Purdue Pharma L.P. (US) 2020-08-12 EP claimed
WO-2019070581-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING DELAYED RELEASE GELLING AGENT COMPOSITIONS PURDUE PHARMA L.P (US) 2019-04-11 WO claimed
US-20190046522-A1 PHARMACEUTICAL FORMULATION CONTAINING IRRITANT PURDUE PHARMA LP (US) 2019-02-14 US claimed
US-10028947-B2 Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant agent PURDUE PHARMA L.P. (US) 2018-07-24 US claimed
US-10022369-B2 Pharmaceutical formulation containing irritant PURDUE PHARMA L.P. (US) 2018-07-17 US claimed
EP-2900272-B1 ABUSE DETERRENT PHARMACEUTICAL COMPOSITION COMPRISING KONJAC GLUCOMANNAN PHARMASCIENCE INC (CA) 2018-06-06 EP claimed
US-20180117158-A1 Abuse Deterrent Pharmaceutical Composition PHARMASCIENCE INC. (CA) 2018-05-03 US claimed
US-20170354654-A1 PHARMACEUTICAL FORMULATION CONTAINING OPIOID AGONIST, OPIOID ANTAGONIST AND IRRITANT AGENT PURDUE PHARMA LP (US) 2017-12-14 US claimed
US-20170296671-A1 Tamper Resistant Pharmaceutical Formulations PURDUE PHARMA LP (US) 2017-10-19 US claimed
US-20170173000-A1 PHARMACEUTICAL FORMULATION CONTAINING IRRITANT PURDUE PHARMA LP (US) 2017-06-22 US claimed
US-20070014732-A1 Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant agent PURDUE PHARMA L.P. (US) 2007-01-18 US claimed
US-7157103-B2 Pharmaceutical formulation containing irritant EURO-CELTIQUE S.A. (LU) 2007-01-02 US claimed
JP-2005501067-A 2005-01-13 JP claimed
EP-1414413-A1 COMPOSITIONS AND METHODS TO PREVENT ABUSE OF OPIOIDS Euro-Celtique S.A. (LU) 2004-05-06 EP claimed
EP-1414418-A1 COMPOSITIONS AND METHODS TO PREVENT ABUSE OF OPIOIDS Euro-Celtique S.A. (LU) 2004-05-06 EP claimed
US-20030068370-A1 Pharmaceutical formulation containing irritant PURDUE PHARMA L.P. 2003-04-10 US claimed
US-20030068392-A1 Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant PURDUE PHARMA L.P. 2003-04-10 US claimed
WO-2003013476-A1 COMPOSITIONS AND METHODS TO PREVENT ABUSE OF OPIOIDS EURO-CELTIQUE S.A. (LU) 2003-02-20 WO claimed
WO-2003013479-A1 COMPOSITIONS AND METHODS TO PREVENT ABUSE OF OPIOIDS EURO-CELTIQUE S.A. (LU) 2003-02-20 WO claimed
EP-0546078-B1 BIRDFOOD CONTAINING CAPSAICIN OR ITS DERIVATIVES OR ANALOGUES US HEALTH (US) 1999-02-24 EP claimed