Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582030 | 0.80 | CA12 (0.36) | DRD2DRD4DRD3MAPK1CA12 | |
| SCHEMBL4435438 | 0.80 | CA12 (0.36) | DRD2DRD4DRD3MAPK1CA12 | |
| SCHEMBL3582035 | 0.80 | CA12 (0.36) | DRD2DRD4DRD3MAPK1CA12 | |
| SCHEMBL3582032 | 0.80 | CA12 (0.36) | DRD2DRD4DRD3MAPK1CA12 | |
| SCHEMBL4436766 | 0.78 | KMT2A (0.38) | DRD2MAPK1CYP2D6KMT2AMAPT | |
| SCHEMBL4444087 | 0.78 | KMT2A (0.38) | DRD2MAPK1CYP2D6KMT2AMAPT | |
| SCHEMBL4447058 | 0.78 | MAPT (0.36) | MAPK1GAACYP2D6KMT2AMAPT | |
| SCHEMBL3585788 | 0.70 | CA12 (0.35) | DRD2DRD4DRD3CA12CA1 | |
| SCHEMBL3585785 | 0.70 | CA12 (0.35) | DRD2DRD4DRD3CA12CA1 | |
| SCHEMBL4444305 | 0.69 | KCNH2 (0.47) | GRM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |