SCHEMBL4435490

SCHEMBL4435490

CCCCCC([Al])(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.39
FDPS P14324 11/20 0.36
GGPS1 O95749 7/20 0.36
SMPD1 P17405 2/20 0.33
CES2 O00748 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11777566 0.97 TSHR (0.44) TSHRTHRBFDPSGGPS1SMPD1
SCHEMBL969293 0.91 TSHR (0.35) TSHRTHRBFDPSLMNA
SCHEMBL11807889 0.85 TSHR (0.50) TSHRTHRBFDPSGGPS1SMPD1
Hydrochloric Acid SCHEMBL1885730 0.75 TSHR (0.38) TSHRTHRBFDPSLMNA
SCHEMBL203543 0.74 OPRM1 (0.32) TSHRTHRBFDPSGGPS1
SCHEMBL10597945 0.69
SCHEMBL4200268 0.69 TSHR (0.44) TSHRTHRBFDPSGGPS1SMPD1
Hexane SCHEMBL30742821 0.69
SCHEMBL8684938 0.67 TSHR (0.50) TSHRTHRBFDPSGGPS1CES2
SCHEMBL21263747 0.67 TSHR (0.42) TSHRTHRBFDPSGGPS1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601664-B2 Olefin polymerization catalyst compositions and method of preparation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2009-10-13 US disclosed
EP-1232161-B1 MIXED METAL ALKOXIDE COMPLEXES AND POLYMERIZATION CATALYSTS MADE THEREFROM UNION CARBIDE CHEM PLASTIC (US) 2007-11-28 EP disclosed
EP-1196454-B1 MAGNESIUM/TITANIUM ALKOXIDE COMPLEXES AND POLYMERIZATION CATALYSTS MADE THEREFROM UNION CARBIDE CHEM PLASTIC (US) 2005-11-16 EP disclosed
EP-1196461-B1 METHODS OF MAKING MAGNESIUM/TRANSITION METAL ALKOXIDE COMPLEXES AND POLYMERIZATION CATALYSTS MADE THEREFROM UNION CARBIDE CHEM PLASTIC (US) 2005-05-04 EP disclosed
US-20050003953-A1 Olefin polymerization catalyst compositions and method of preparation W. R. GRACE & CO.-CONN. 2005-01-06 US disclosed
US-6759362-B2 SOLID COMPLEX CATALYST PRECURSOR THAT FORMS A PROCATALYST WHEN CONTACTED WITH A HALOGENATING AGENT AND OPTIONALLY AN ELECTRON DONOR; PROCATALYST IS CONVERTED TO AN OLEFIN POLYMERIZATION CATALYST BY CONTACTING WITH A COCATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2004-07-06 US disclosed
EP-1401884-A1 OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND METHOD OF PREPERATION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2004-03-31 EP disclosed
CN-1423653-A Mixed metal alkoxide complexes and polymerization catalysts made therefrom UNION CARBIDE CHEM PLASTIC (US) 2003-06-11 CN disclosed
US-20030087755-A1 Olefin polymerization catalyst compositions and method of preparation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2003-05-08 US disclosed
EP-0908469-B1 Olefin polymerization catalyst precursor UNION CARBIDE CHEM PLASTIC (US) 2003-05-02 EP disclosed
US-5151399-A Magnesium, a titanium tetraalkoxide, a alkyl borate ester and an alkanol SHELL OIL COMPANY (US) 1992-09-29 US disclosed
US-5146028-A Selective catalyst, high bulk density polymer SHELL OIL COMPANY (US) 1992-09-08 US disclosed
US-5141910-A Magnesium titanium complex alkoxide catalyst precursor SHELL OIL COMPANY (US) 1992-08-25 US disclosed
US-5132263-A Polymerization catalysts of magnesium alkoxide, titanium tetraalkoxide and phenolic compounds as coordination catalysts SHELL OIL COMPANY (US) 1992-07-21 US disclosed
US-5124298-A Procatalyst of magnesium alkoxide, titanium tetraalkoxide, titanium halide, and phenolic compound; cocatalyst; selectivity control agent SHELL OIL COMPANY (US) 1992-06-23 US disclosed
EP-0481749-A2 Olefin polymerization catalyst SHELL OIL COMPANY (US) 1992-04-22 EP disclosed
US-5106806-A Precursor solution containing complex magnesium and titanium alkoxide, phenolic compound SHELL OIL COMPANY (US) 1992-04-21 US disclosed
US-5082907-A Coordination catalysts SHELL OIL COMPANY (US) 1992-01-21 US disclosed
US-5077357-A Titanium procatalyst and organoaluminum cocatalyst SHELL OIL COMPANY (US) 1991-12-31 US disclosed
US-5066737-A Complex Titanium-Magnesium Procatalyst, Organoaluminum Cocatalyst And A Selectivity Control Agent SHELL OIL COMPANY (US) 1991-11-19 US disclosed