Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908592 | 1.00 | FASN (0.35) | FASNCCR5SMN1; SMN2TSHRMME | |
| SCHEMBL598408 | 1.00 | FASN (0.35) | FASNCCR5SMN1; SMN2TSHRMME | |
| SCHEMBL597903 | 1.00 | FASN (0.35) | FASNCCR5SMN1; SMN2TSHRMME | |
| SCHEMBL597446 | 0.88 | FASN (0.36) | FASNCCR5SMN1; SMN2TSHRMME | |
| SCHEMBL597445 | 0.88 | FASN (0.36) | FASNCCR5SMN1; SMN2TSHRMME | |
| SCHEMBL598277 | 0.87 | L3MBTL1 (0.37) | CCR5SMN1; SMN2TSHRADAM17HPGD | |
| SCHEMBL597038 | 0.87 | L3MBTL1 (0.37) | CCR5SMN1; SMN2TSHRADAM17HPGD | |
| SCHEMBL1908590 | 0.87 | L3MBTL1 (0.37) | CCR5SMN1; SMN2TSHRADAM17HPGD | |
| SCHEMBL598349 | 0.76 | HCRTR1 (0.39) | CCR5SMN1; SMN2TSHRMMEACE | |
| SCHEMBL598350 | 0.76 | HCRTR1 (0.39) | CCR5SMN1; SMN2TSHRMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121578-A2 | NEW PROCESS | Novartis AG (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083967-A2 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2008-07-17 | — | — | WO | disclosed |