Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18143563 | 0.80 | NR1H2 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL250237 | 0.79 | ESR1 (0.37) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL4434894 | 0.76 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL890423 | 0.76 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL10586251 | 0.75 | ESR1 (0.35) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL6157102 | 0.74 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL4445118 | 0.74 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL2678713 | 0.72 | ESR1 (0.33) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL2678611 | 0.72 | NR1H2 (0.34) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL8785246 | 0.72 | ESR1 (0.32) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125833-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | Wacker Chemie AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| EP-2125834-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | Wacker Chemie AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008090013-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008090012-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2008-07-31 | — | — | WO | disclosed |