Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188350 | 0.77 | HTR2A (0.31) | — | |
| SCHEMBL5604498 | 0.70 | — | — | |
| SCHEMBL4440338 | 0.67 | — | — | |
| SCHEMBL12490120 | 0.66 | — | — | |
| SCHEMBL18422837 | 0.65 | — | — | |
| SCHEMBL15226238 | 0.63 | — | — | |
| SCHEMBL1561926 | 0.62 | — | — | |
| SCHEMBL1417167 | 0.60 | — | — | |
| SCHEMBL16240021 | 0.60 | — | — | |
| SCHEMBL12928765 | 0.60 | RIPK1 (0.85) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121609-A1 | SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008091818-A1 | SUBSTITUTED ARYLCYCLOPENTENES AS THERAPEUTIC AGENTS | ALLERGAN, INC. (US) | 2008-07-31 | — | — | WO | claimed |