Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435931 | 1.00 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL3780053 | 0.96 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL3778347 | 0.96 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL3776096 | 0.88 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL3776094 | 0.88 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL13017909 | 0.88 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL13063002 | 0.85 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL3772539 | 0.85 | ALDH1A1 (0.48) | TRPV1 | |
| SCHEMBL3772541 | 0.85 | ALDH1A1 (0.48) | TRPV1 | |
| SCHEMBL3772495 | 0.85 | TRPV1 (0.44) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054411-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008013414-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2008-01-31 | — | — | WO | disclosed |