Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BHMT | Q93088 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301256 | 1.00 | GPR84 (0.52) | GPR84ACE2CA2MAPK1MAPT | |
| SCHEMBL905453 | 1.00 | GPR84 (0.52) | GPR84ACE2CA2MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL27778084 | 0.98 | GPR84 (0.50) | GPR84ACE2CA2MAPK1MAPT | |
| SCHEMBL28055317 | 0.98 | GPR84 (0.50) | GPR84ACE2CA2MAPK1MAPT | |
| SCHEMBL5858405 | 0.94 | ACE2 (0.60) | GPR84ACE2CA2MAPK1MAPT | |
| SCHEMBL544052 | 0.93 | GPR84 (0.61) | GPR84ACE2MAPTAKR1B1PPARG | |
| SCHEMBL30882121 | 0.93 | GPR84 (0.61) | GPR84ACE2MAPTAKR1B1PPARG | |
| SCHEMBL23930717 | 0.91 | GPR84 (0.64) | GPR84ACE2MAPTPPARGPPARD | |
| SCHEMBL17772493 | 0.91 | GPR84 (0.64) | GPR84ACE2MAPTPPARGPPARD | |
| SCHEMBL22612526 | 0.91 | GPR84 (0.64) | GPR84ACE2MAPTPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894772-A | Preparation method of key intermediate of high optical purity limaprost | 常州博海威医药科技股份有限公司 | 2024-11-05 | — | — | CN | claimed |
| EP-0638059-A1 | PROCESS FOR THE PREPARATION OF 3(S)-METHYLHEPTANOIC ACID AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1995-02-15 | — | — | EP | claimed |
| US-5286904-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1994-02-15 | — | — | US | claimed |
| WO-1993022269-A1 | PROCESS FOR THE PREPARATION OF 3(S)-METHYLHEPTANOIC ACID AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1993-11-11 | — | — | WO | claimed |
| US-5248820-A | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1993-09-28 | — | — | US | claimed |
| WO-1988001613-A1 | CRYSTALLINE N-(S-3-METHYLHEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE, AND PROCESSES AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1988-03-10 | — | — | WO | claimed |
| WO-1988001612-A1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYL-HEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1988-03-10 | — | — | WO | claimed |
| EP-0259084-A2 | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1988-03-09 | — | — | EP | claimed |
| EP-0258032-A2 | Processes and intermediates for N-(S-3-alkylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1988-03-02 | — | — | EP | claimed |
| EP-0227078-A1 | Process for preparing (S)-alpha-methylarylacetic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-07-01 | — | — | EP | claimed |
| CN-121472200-A | Nitrilase mutant and application thereof in preparation of (S) -3-methylheptanoic acid | 杭州微远生物科技有限公司 | 2026-02-06 | — | — | CN | disclosed |
| CN-121472200-A | Nitrilase mutant and application thereof in preparation of (S) -3-methylheptanoic acid | 杭州微远生物科技有限公司 | 2026-02-06 | — | — | CN | disclosed |
| CN-118894772-A | Preparation method of key intermediate of high optical purity limaprost | 常州博海威医药科技股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118894772-A | Preparation method of key intermediate of high optical purity limaprost | 常州博海威医药科技股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-0227306-A2 | Peptide immunostimulants | PFIZER INC. (US) | 1987-07-01 | — | — | EP | disclosed |
| EP-0227078-A1 | Process for preparing (S)-alpha-methylarylacetic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-07-01 | — | — | EP | disclosed |
| US-4564620-A | 5,6,7,-Trinor-4,8-inter-m-phenylene PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0060640-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1985-11-13 | — | — | EP | disclosed |
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |