Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4430700 | 0.81 | CYP2C19 (0.35) | CYP2C19KDM4ECYP1A2ALOX15GABRP | |
| SCHEMBL1414757 | 0.72 | CYP2C19 (1.00) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL17048783 | 0.68 | — | — | |
| SCHEMBL25287945 | 0.64 | CYP2C19 (0.70) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL25475466 | 0.64 | CYP2C19 (0.79) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11636846 | 0.64 | CYP2C19 (0.70) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL24867690 | 0.63 | CYP2C19 (0.67) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL23677473 | 0.63 | CYP2C19 (0.75) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL22160003 | 0.63 | CYP2C19 (0.67) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL24867996 | 0.63 | CYP2C19 (0.75) | CYP2C19APLNRKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124944-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-12-02 | — | — | EP | claimed |
| WO-2008111010-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-09-18 | — | — | WO | claimed |