Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 12/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930739 | 0.94 | KCNH2 (0.51) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL9968662 | 0.93 | KCNH2 (0.43) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL13429591 | 0.91 | KCNH2 (0.42) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL13429589 | 0.89 | KCNH2 (0.46) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL13429587 | 0.88 | KCNH2 (0.37) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL13429590 | 0.88 | KCNH2 (0.37) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL9930077 | 0.87 | KCNH2 (0.36) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL13429499 | 0.86 | KCNH2 (0.39) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL13456680 | 0.85 | KCNH2 (0.37) | KCNH2WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL9964852 | 0.84 | KCNH2 (0.37) | KCNH2WNT1GSK3BDYRK1APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |