Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 6/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.31 |
| ▸ | SKP1 | P63208 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968662 | 0.93 | KCNH2 (0.43) | KCNH2F10PDE10AGSK3BDYRK1A | |
| SCHEMBL4436007 | 0.91 | KCNH2 (0.45) | KCNH2F10PDE10AGSK3BDYRK1A | |
| SCHEMBL9930739 | 0.90 | KCNH2 (0.51) | KCNH2F10PDE10AGSK3BDYRK1A | |
| SCHEMBL13429563 | 0.88 | KCNH2 (0.42) | KCNH2F10ACACBACACACYP11B1 | |
| SCHEMBL13429589 | 0.85 | KCNH2 (0.46) | KCNH2CYP11B1CYP11B2PDE10AGSK3B | |
| SCHEMBL13429587 | 0.84 | KCNH2 (0.37) | KCNH2CYP11B1CYP11B2PDE10AGSK3B | |
| SCHEMBL13429499 | 0.84 | KCNH2 (0.39) | KCNH2PDE10AGSK3BDYRK1AWNT1 | |
| SCHEMBL13429590 | 0.83 | KCNH2 (0.37) | KCNH2CYP11B1CYP11B2PDE10AGSK3B | |
| SCHEMBL9968533 | 0.83 | MAOB (0.38) | KCNH2CYP11B1CYP11B2PDE10A | |
| SCHEMBL13456680 | 0.82 | KCNH2 (0.37) | KCNH2PDE10AGSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | GORDEEV MIKHAIL FEDOROVICH | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069441-A1 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | IDO1, IDO2, INMT | KCNH2 1145/4885F10 3746/4885ACACB 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.