SCHEMBL443601

SCHEMBL443601

Fc1nc(F)c(F)c(-c2c(F)c(F)nc(F)c2F)c1F

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13789774 0.93 MEN1 (0.42) MEN1MAPTHTTKMT2A
SCHEMBL19151729 0.82 MEN1 (0.40) MEN1MAPTHTTKMT2A
SCHEMBL19131122 0.82 MEN1 (0.41) MEN1MAPTHTTKMT2A
SCHEMBL188694 0.78 MEN1 (0.41) MEN1MAPTHTTKMT2A
SCHEMBL4311227 0.71 MEN1 (0.33) MEN1MAPTHTTKMT2A
SCHEMBL23189461 0.71 NISCH (0.42) MEN1MAPTKMT2A
SCHEMBL3180199 0.69 MEN1 (0.36) MEN1MAPTHTTKMT2A
SCHEMBL7028015 0.69 MEN1 (0.36) MEN1MAPTHTTKMT2A
SCHEMBL24910013 0.69 MEN1 (0.36) MEN1MAPTHTTKMT2A
SCHEMBL7022108 0.69 MEN1 (0.36) MEN1MAPTHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9207234-B2 Thermally stable SERS taggants SICPA HOLDING SA (CH) 2015-12-08 US claimed
EP-2433121-A1 THERMALLY STABLE SERS TAGGANTS Cabot Security Materials Inc. (US) 2012-03-28 EP claimed
US-20120062886-A1 Thermally Stable SERS Taggants CABOT SECURITY MATERIALS INC. (US) 2012-03-15 US claimed
WO-2010135351-A1 THERMALLY STABLE SERS TAGGANTS OXONICA MATERIALS INC. (US) 2010-11-25 WO claimed
US-10450205-B2 Metal organic framework with perfluorinated linker YOUNGSTOWN STATE UNIVERSITY (US) 2019-10-22 US disclosed
US-20170204118-A1 METAL ORGANIC FRAMEWORK WITH PERFLUORINATED LINKER YOUNGSTOWN STATE UNIVERSITY (US) 2017-07-20 US disclosed
US-9207234-B2 Thermally stable SERS taggants SICPA HOLDING SA (CH) 2015-12-08 US disclosed
EP-2433121-A1 THERMALLY STABLE SERS TAGGANTS Cabot Security Materials Inc. (US) 2012-03-28 EP disclosed
US-20120062886-A1 Thermally Stable SERS Taggants CABOT SECURITY MATERIALS INC. (US) 2012-03-15 US disclosed
WO-2010135351-A1 THERMALLY STABLE SERS TAGGANTS OXONICA MATERIALS INC. (US) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204118-A1 METAL ORGANIC FRAMEWORK WITH PERFLUORINATED LINKER AFF2, HNRNPF, SLC30A7 MEN1 4214/4885MAPT 880/4885HTT 2032/4885
US-10450205-B2 Metal organic framework with perfluorinated linker AFF2, HNRNPF, SLC30A7 MEN1 4214/4885MAPT 880/4885HTT 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.