SCHEMBL7028015

SCHEMBL7028015

Fc1nc(F)c(F)c(Cl)c1F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10744284 0.87 MEN1 (0.37) MEN1KMT2AMAPTHTTGAA
SCHEMBL8465838 0.86 MEN1 (0.31) MEN1KMT2AMAPTHTTGAA
SCHEMBL502245 0.80 MEN1 (0.37) MEN1KMT2AMAPTHTTGAA
SCHEMBL17156504 0.80 MEN1 (0.34) MEN1KMT2AGAA
SCHEMBL8737324 0.80 CES2 (0.31)
SCHEMBL23258946 0.80
SCHEMBL282140 0.79 MEN1 (0.35) MEN1KMT2AMAPTHTTGAA
SCHEMBL9320239 0.78 MEN1 (0.32) MEN1KMT2AMAPTHTT
SCHEMBL9513607 0.76 MEN1 (0.34) MEN1KMT2AGAA
SCHEMBL9787166 0.74 MEN1 (0.32) MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11388901-B2 Herbicidal azines BASF SE (DE) 2022-07-19 US disclosed
US-20210112811-A1 HERBICIDAL AZINES BASF SE (DE) 2021-04-22 US disclosed
US-10676423-B2 Structure and synthesis of highly fluorinated amino acid derivatives THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) 2020-06-09 US disclosed
US-20200123099-A1 Structure and Synthesis of Highly Fluorinated Amino Acid Derivatives UNIV OKLAHOMA STATE (US) 2020-04-23 US disclosed
WO-2018166822-A1 HERBICIDAL AZINES BASF SE (DE) 2018-09-20 WO disclosed
WO-2018156500-A1 STRUCTURE AND SYNTHESIS OF HIGHLY FLUORINATED AMINO ACID DERIVATIVES THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) 2018-08-30 WO disclosed
EP-0749433-B1 (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY SYNGENTA LTD (GB) 2003-05-07 EP disclosed
EP-0723545-B1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LAB (US) 2002-05-08 EP disclosed
WO-2000010998-A2 PYRIDONE ANTIBIOTIC WITH IMPROVED SAFETY PROFILE ABBOTT LABORATORIES (US) 2000-03-02 WO disclosed
US-5977133-A Pyridone antibiotic with improved safety profile ABBOTT LABORATORIES (US) 1999-11-02 US disclosed
US-5726182-A TREATMENT OF BACTERIAL INFECTIONS ABBOTT LABORATORIES (US) 1998-03-10 US disclosed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed
US-5705516-A NEMATOCIDES, INSECTICIDES, ACARICIDES ZENECA LIMITED (GB) 1998-01-06 US disclosed
US-5599816-A BACTERICIDE ABBOTT LABORATORIES (US) 1997-02-04 US disclosed
EP-0749433-A1 (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY ZENECA LIMITED (GB) 1996-12-27 EP disclosed
WO-1996039407-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-12-12 WO disclosed
US-5580872-A ADMINISTERING IN THE TREATMENT OF BACTERIAL INFECTIONS ABBOTT LABORATORIES (US) 1996-12-03 US disclosed
EP-0723545-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-07-31 EP disclosed
WO-1995024403-A1 (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY ZENECA LIMITED (GB) 1995-09-14 WO disclosed
WO-1995010519-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11388901-B2 Herbicidal azines DDT, AOC1, AZI2 MEN1 2257/4885KMT2A 603/4885MAPT 3313/4885
US-20200123099-A1 Structure and Synthesis of Highly Fluorinated Amino Acid Derivatives PFAS, BCAT2, SLC7A1 MEN1 2094/4885KMT2A 878/4885MAPT 1513/4885
US-20210112811-A1 HERBICIDAL AZINES DDT, AOC1, AZI2 MEN1 2257/4885KMT2A 603/4885MAPT 3313/4885
US-10676423-B2 Structure and synthesis of highly fluorinated amino acid derivatives PFAS, BCAT2, SLC7A1 MEN1 2094/4885KMT2A 878/4885MAPT 1513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.