⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905022 | 0.78 | — | — | |
| SCHEMBL19844920 | 0.76 | — | — | |
| SCHEMBL21896695 | 0.74 | — | — | |
| SCHEMBL25174537 | 0.72 | — | — | |
| SCHEMBL19844924 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL17649646 | 0.68 | — | — | |
| SCHEMBL31653948 | 0.68 | — | — | |
| SCHEMBL3102138 | 0.67 | — | — | |
| SCHEMBL8845788 | 0.67 | — | — | |
| SCHEMBL19844921 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134726-A1 | IMPROVED PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES | Momentive Performance Materials Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008115190-A1 | IMPROVED PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| US-20080234441-A1 | PROCESS FOR PRODUCING BIS-(AMINOALKYL)-POLYSILOXANES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-25 | — | — | US | disclosed |
| CN-100368415-C | 6-alkenyl-, 6-alkynyl-and 6-epoxy-EPOTHILONE derivatives, method for the production thereof and use thereof | SCHERING AG (DE) | 2008-02-13 | — | — | CN | disclosed |
| CN-1209360-C | 16-halogen-epothilones derivatives, preparation method and medical application thereof | SCHERIING AG (DE) | 2005-07-06 | — | — | CN | disclosed |
| CN-1349534-A | 6-alkenyl-, 6-alkinyl-and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations | SCHERING AG (DE) | 2002-05-15 | — | — | CN | disclosed |
| CN-1341115-A | 16-halogen-epothilones derivatives, preparation method and medical application thereof | SCHERIING AG (DE) | 2002-03-20 | — | — | CN | disclosed |