Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 7/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060340 | 0.77 | HCAR3 (0.49) | IDH1DPP4DPP7MEN1KMT2A | |
| SCHEMBL646539 | 0.77 | DPP4 (0.47) | IDH1DPP4DPP7MEN1KMT2A | |
| SCHEMBL15471096 | 0.77 | DPP4 (0.45) | IDH1DPP4DPP7GSK3BDPP8 | |
| SCHEMBL6638863 | 0.77 | DPP4 (0.53) | IDH1DPP4DPP7MEN1KMT2A | |
| SCHEMBL13617155 | 0.75 | DPP4 (0.43) | IDH1DPP4DPP7GSK3BCCR6 | |
| SCHEMBL3049238 | 0.74 | HCAR3 (0.51) | IDH1DPP4DPP7GSK3BDPP8 | |
| SCHEMBL1344707 | 0.74 | IDH1 (0.43) | IDH1DPP4DPP7MEN1KMT2A | |
| SCHEMBL14184982 | 0.74 | MEN1 (0.42) | IDH1DPP4MEN1KMT2ACCR6 | |
| SCHEMBL21167755 | 0.73 | HCAR3 (0.53) | IDH1DPP4DPP7MEN1KMT2A | |
| SCHEMBL6125342 | 0.73 | DPP4 (0.48) | IDH1DPP4DPP7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137188-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008113469-A2 | SUBSTITUTED IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-25 | — | — | WO | disclosed |