Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL4990367 | 0.88 | TDP1 (0.56) | ALOX15TDP1HSD17B10TTRPTPRC | |
| SCHEMBL9181081 | 0.85 | CA12 (0.49) | PBRM1TDP1TTRPTPRCKMT2A | |
| Terephthalic Acid SCHEMBL1292728 | 0.84 | TTR (0.55) | ALOX15TDP1HSD17B10TTRPTPRC | |
| 3-Aminobenzoic Acid SCHEMBL28231735 | 0.84 | PBRM1 (0.70) | PBRM1TDP1HSD17B10KMOKMT2A | |
| 3-Aminobenzoic Acid SCHEMBL29367812 | 0.84 | PBRM1 (0.69) | PBRM1HSD17B10KMOKMT2ACA12 | |
| 3-Aminobenzoic Acid SCHEMBL27648 | 0.84 | PBRM1 (0.69) | PBRM1HSD17B10KMOKMT2ACA12 | |
| 3-Aminobenzoic Acid SCHEMBL8003706 | 0.84 | PBRM1 (0.69) | PBRM1HSD17B10KMOKMT2ACA12 | |
| 3-Aminobenzoic Acid SCHEMBL11796891 | 0.82 | PBRM1 (0.67) | PBRM1HSD17B10KMOKMT2ACA12 | |
| 3-Aminobenzoic Acid SCHEMBL2296707 | 0.82 | PBRM1 (0.67) | PBRM1HSD17B10KMOKMT2ACA12 | |
| Phthalic Anhydride SCHEMBL5450495 | 0.82 | TSHR (0.64) | ALOX15TDP1HSD17B10TTRPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8241371-B2 | Concurrent precipitation of active material and crystal former from solution or suspension in presence of supercritical fluid such as carbon dioxide | THAR PHARMACEUTICALS, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| EP-2117666-A1 | METHOD OF CREATING CRYSTALLINE SUBSTANCES | Thar Pharmaceuticals Inc. (US) | 2009-11-18 | — | — | EP | disclosed |
| US-20080280858-A1 | METHOD OF CREATING CRYSTALLINE SUBSTANCES | THAR PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| WO-2008096144-A1 | METHOD OF CREATING CRYSTALLINE SUBSTANCES | THAR PHARMACEUTICALS INC. (US) | 2008-08-14 | — | — | WO | disclosed |