Isophthalic Acid

Isophthalic Acid

SCHEMBL4990367

O=C(O)c1cccc(C(=O)O)c1.O=C1OC(=O)c2ccccc21

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
ALOX15 P16050 1/20 0.56
TTR P02766 1/20 0.53
HSD17B10 Q99714 1/20 0.53
KMO O15229 1/20 0.52
PTPRC P08575 2/20 0.52
KMT2A Q03164 2/20 0.50
DAO P14920 1/20 0.50
TSHR P16473 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA6 P23280 1/20 0.50
CA9 Q16790 1/20 0.50
POLB P06746 1/20 0.49
AKR1C3 P42330 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TYMS P04818 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL1292728 0.96 TTR (0.55) TDP1ALOX15TTRHSD17B10KMO
Phthalic Anhydride SCHEMBL28856609 0.92 ALOX15 (0.61) TDP1ALOX15TTRHSD17B10PTPRC
Phthalic Anhydride SCHEMBL11139486 0.90 ALOX15 (0.45) TDP1ALOX15TTRHSD17B10KMO
Phthalic Anhydride SCHEMBL5450495 0.90 TSHR (0.64) TDP1ALOX15TTRHSD17B10PTPRC
Isophthalic Acid SCHEMBL11135539 0.89 TTR (0.55) TDP1TTRPTPRCKMT2ACA12
Phthalic Anhydride SCHEMBL4436162 0.88 PBRM1 (0.56) TDP1ALOX15TTRHSD17B10KMO
Phthalic Anhydride SCHEMBL5930931 0.86 TTR (0.67) TDP1ALOX15TTRPTPRCKMT2A
Terephthalic Acid SCHEMBL4204274 0.85 ALOX15 (0.64) TDP1ALOX15TTRHSD17B10PTPRC
Isophthalic Acid SCHEMBL9679148 0.85 DAO (0.62) TDP1TTRHSD17B10KMOPTPRC
Benzoic Acid SCHEMBL27945375 0.85 TTR (0.59) TDP1ALOX15TTRPTPRCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0942939-A1 THERMOPLASTIC-BASED MINERAL-LIKE COMPOSITIONS Safas Corporation (US) 1999-09-22 EP claimed
WO-1998014486-A1 THERMOPLASTIC-BASED MINERAL-LIKE COMPOSITIONS SAFAS CORPORATION (US) 1998-04-09 WO claimed
EP-0075954-B1 CURABLE MOLDING COMPOSITIONS UNION CARBIDE CORPORATION (US) 1988-08-10 EP claimed
EP-0075954-A1 Curable molding compositions UNION CARBIDE CORPORATION (US) 1983-04-06 EP claimed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-20080160288-A1 Method for Impregnating Lignocellulosic Materials with Effect Agents BASF AKTIENGESELLSCHAFT (DE) 2008-07-03 US disclosed
US-6586361-B1 Comprising vanadium oxide, titanium dioxide, cesium compound, phosphorous compound, and antimony oxide; carboxylation, anhydriding BASF AKTIENGESELLSCHAFT (DE) 2003-07-01 US disclosed
US-4303567-A PEROXY-FREE PROMOTERS BAYER AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed