Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795667 | 0.86 | TSHR (0.53) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL11317319 | 0.84 | KDM4E (0.43) | TSHRLMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8423616 | 0.80 | TSHR (0.52) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL4356482 | 0.79 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL28075392 | 0.79 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL21360132 | 0.79 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL21817064 | 0.79 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL17063567 | 0.78 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL14660709 | 0.78 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL6274865 | 0.78 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114353-A1 | METHOD FOR IMPARTING A COSMETIC OR THERAPEUTIC BENEFIT TO A TOPICAL SURFACE AND PROCESS FOR MAKING | AVON PRODUCTS, INC. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008082750-A1 | METHOD FOR IMPARTING A COSMETIC OR THERAPEUTIC BENEFIT TO A TOPICAL SURFACE AND PROCESS FOR MAKING | AVON PRODUCTS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |