Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423616 | 0.93 | TSHR (0.52) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL4436175 | 0.86 | TSHR (0.55) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL1009862 | 0.78 | — | — | |
| SCHEMBL4356482 | 0.76 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL21817064 | 0.76 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL21360132 | 0.76 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL28075392 | 0.76 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL17063567 | 0.76 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL14660709 | 0.76 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL6274865 | 0.76 | TSHR (0.60) | TSHRHCAR2NAAARAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002848-A | Thermoplastic resin particles with a positive charge, a carboxylic acid adjuvants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0417779-A2 | Substituted carboxylic acids as adjuvants for positive electrostatic liquid developers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |