SCHEMBL443620

SCHEMBL443620

CCCCc1ccc(OP(Oc2ccc(CCCC)c(CCCC)c2CCCC)Oc2ccc(CCCC)c(CCCC)c2CCCC)c(CCCC)c1CCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.37
NCEH1 Q6PIU2 1/20 0.35
CTRC Q99895 1/20 0.34
HTT P42858 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
RAD52 P43351 1/20 0.33
ALOX5 P09917 2/20 0.33
PTGS2 P35354 1/20 0.33
TSHR P16473 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HPGD P15428 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10790735 0.93 TYR (0.42) TYRHTTMEN1MAPTKMT2A
SCHEMBL130577 0.93 TYR (0.42) TYRHTTMEN1MAPTKMT2A
SCHEMBL10786270 0.93 TYR (0.42) TYRHTTMEN1MAPTKMT2A
SCHEMBL443621 0.86 TYR (0.39) TYRNCEH1CTRCHTTMEN1
SCHEMBL448419 0.85 KDM4E (0.32) NCEH1HPGDKDM4EALDH1A1
SCHEMBL28916682 0.85 TYR (0.41) TYRNCEH1CTRCHTTMEN1
SCHEMBL500088 0.84 PTGS2 (0.45) HTTMAPK1NPSR1ALOX5PTGS2
SCHEMBL30196112 0.84 PTGS2 (0.45) HTTMAPK1NPSR1ALOX5PTGS2
SCHEMBL29857967 0.84 PTGS2 (0.45) HTTMAPK1NPSR1ALOX5PTGS2
SCHEMBL10790741 0.80 TYR (0.44) TYRHTTMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
CN-110573566-B High efficiency phosphorus stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives 弗劳恩霍夫应用研究促进协会 2021-07-30 CN disclosed
US-10829708-B2 Composition and method for preventing or reducing engine knock and pre-ignition in high compression spark ignition engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-11-10 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020139333-A1 FORMULATION APPROACH TO EXTEND THE HIGH TEMPERATURE PERFORMANCE OF LITHIUM COMPLEX GREASES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-07-02 WO disclosed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-20080020954-A1 High viscosity novel base stock lubricant extreme viscosity blends HAIGH HEATHER M 2008-01-24 US disclosed
US-20070298990-A1 High viscosity metallocene catalyst pao novel base stock lubricant blends EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145923-A1 NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
US-20070289897-A1 Novel base stock lubricant blends CAREY JAMES T 2007-12-20 US disclosed
EP-1439168-B1 Process for the preparation of acyloxybenzenesulphonates CLARIANT PRODUKTE DEUTSCHLAND (DE) 2007-10-03 EP disclosed
US-20020010103-A1 Lubricating oil composition having excellent thermal stability, extreme pressure resistance and anti-wear performance CHEVRON ORONITE JAPAN LIMITED (JP) 2002-01-24 US disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed
US-3976551-A CONJUGATED DIENE POLYMER, RADIATION PHILLIPS PETROLEUM COMPANY (US) 1976-08-24 US disclosed