Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816814 | 0.87 | MAPT (0.54) | POLBKDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL2818082 | 0.80 | MAPT (0.53) | POLBKDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL2813976 | 0.78 | PDE4D (0.60) | POLBKDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL2869412 | 0.78 | PDE5A (0.55) | POLBKDM4EALDH1A1HPGDCHEK1 | |
| SCHEMBL2816013 | 0.74 | MEN1 (0.60) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL23144868 | 0.73 | DHODH (0.46) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4436319 | 0.73 | L3MBTL1 (0.35) | KMT2ACYP3A4CYP2C19 | |
| SCHEMBL2874235 | 0.72 | PDE4D (0.60) | POLBKDM4EALDH1A1CHEK1PIM1 | |
| SCHEMBL27796944 | 0.72 | MEN1 (0.51) | POLBKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL2816049 | 0.71 | POLB (0.62) | POLBALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |