Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F11 | P03951 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436565 | 0.86 | F10 (0.42) | F10F2F11MAPK1 | |
| SCHEMBL4429983 | 0.85 | F10 (0.38) | F10F2F11MAPK1 | |
| SCHEMBL4438714 | 0.85 | F10 (0.43) | F10MAPK1 | |
| SCHEMBL4442146 | 0.85 | F10 (0.38) | F10F2F11MAPK1 | |
| SCHEMBL4440745 | 0.83 | MAPK1 (0.41) | F10F2F11MAPK1 | |
| SCHEMBL3304020 | 0.81 | F10 (0.40) | F10F2F11MAPK1 | |
| SCHEMBL4436005 | 0.77 | F10 (0.40) | F10F2F11MAPK1 | |
| SCHEMBL3450031 | 0.73 | F10 (0.47) | F10F2F11MAPK1 | |
| SCHEMBL3448349 | 0.72 | F10 (0.43) | F10F2F11MAPK1 | |
| SCHEMBL4582592 | 0.72 | F10 (0.42) | F10F2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2132193-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | Boehringer Ingelheim International GmbH (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |