Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817652 | 0.85 | KMT2A (0.69) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2814975 | 0.84 | KMT2A (0.59) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2815498 | 0.78 | KMT2A (0.67) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2814801 | 0.75 | KMT2A (0.62) | KMT2AKDM4EMEN1ALDH1A1NPC1 | |
| SCHEMBL2817053 | 0.75 | TSHR (0.71) | KMT2AKDM4EMEN1NPC1RAB9A | |
| SCHEMBL2817622 | 0.71 | TSHR (0.64) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2814692 | 0.70 | KMT2A (0.66) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2819698 | 0.70 | KMT2A (0.80) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2814616 | 0.70 | KMT2A (0.76) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL2817570 | 0.70 | KMT2A (0.76) | KMT2AKDM4EMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |