Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 18/20 | 0.48 |
| ▸ | PGR | P06401 | 15/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436716 | 0.85 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL4435058 | 0.85 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL4440564 | 0.85 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL4442395 | 0.84 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL4438783 | 0.83 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL4441939 | 0.81 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL4435062 | 0.81 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL4440922 | 0.79 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL4439562 | 0.79 | NR3C1 (0.47) | NR3C1NR3C2PGR | |
| SCHEMBL4442287 | 0.79 | NR3C1 (0.49) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136811-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-12-30 | — | — | EP | claimed |
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | claimed |
| EP-2136811-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |