Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232642 | 0.81 | CPA1 (0.46) | CPA1TRPA1NPC1TP53RAB9A | |
| SCHEMBL5981148 | 0.81 | CPA1 (0.50) | CPA1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL28259287 | 0.81 | CPA1 (0.50) | CPA1CYP1A2TRPA1ALPIPKM | |
| SCHEMBL8977883 | 0.81 | CPA1 (0.59) | CPA1EPHX1NPC1 | |
| SCHEMBL9279472 | 0.81 | CPA1 (0.46) | CPA1CYP1A2EPHX1ALPIPKM | |
| SCHEMBL28507507 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHR | |
| SCHEMBL9756637 | 0.79 | CPA1 (0.49) | CPA1CYP1A2EPHX1ALDH1A1NPC1 | |
| Ammonia Solution, Strong SCHEMBL6014441 | 0.79 | CPA1 (0.45) | CPA1TRPA1NPC1TP53RAB9A | |
| SCHEMBL27937964 | 0.79 | CPA1 (0.41) | CPA1CYP1A2EPHX1ALDH1A1ALPI | |
| SCHEMBL6014438 | 0.78 | CPA1 (0.44) | CPA1EPHX1ALDH1A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121603-A2 | 6' SUBSTITUTED INDOLE AND INDAZOLE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | Memory Pharmaceuticals Corporation (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008101247-A2 | 6 ' SUBSTITUTED INDOLE AND INDAZOLE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-08-21 | — | — | WO | disclosed |