Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL18049528 | 0.92 | CHRM2 (0.56) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL5728905 | 0.90 | CHRM2 (0.58) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL1723411 | 0.90 | CHRM2 (0.58) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL4870895 | 0.88 | CHRM2 (0.60) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL20483452 | 0.88 | CHRM2 (0.64) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8187341 | 0.86 | CHRM2 (0.58) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL10721099 | 0.80 | HRH3 (0.46) | CHRM2CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL20967986 | 0.79 | CHRM2 (0.54) | CHRM2CHRM4CHRM5ALDH1A1LMNA | |
| SCHEMBL9023345 | 0.79 | CHRM2 (0.54) | CHRM2CHRM4CHRM5ALDH1A1LMNA | |
| SCHEMBL15425876 | 0.79 | KMT2A (0.54) | CHRM2CHRM4CHRM5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118109-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008112473-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |