Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901571 | 0.89 | KMT2A (0.71) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL3949532 | 0.88 | KMT2A (0.78) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2721612 | 0.83 | MAPT (0.73) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2362772 | 0.83 | KMT2A (0.82) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL4429131 | 0.82 | MAPT (0.76) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5390989 | 0.82 | MAPT (0.71) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL4429130 | 0.82 | MAPT (0.71) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL30739719 | 0.82 | MAPT (0.71) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL4429129 | 0.81 | MAPT (0.69) | MAPTRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL94630 | 0.81 | MAPT (0.69) | MAPTRAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049137-A2 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES | The Regents of the University of California (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008021088-A2 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2008-02-21 | — | — | WO | disclosed |