SCHEMBL4437119

SCHEMBL4437119

Fc1c(F)c(C(F)(F)F)c(F)c(F)c1OC(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31171303 0.83 CA1 (0.32)
SCHEMBL23846262 0.80 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL3094424 0.78 SMN1; SMN2 (0.54) TSHRSMN1; SMN2
SCHEMBL312355 0.76 SMN1; SMN2 (0.42) TSHRSMN1; SMN2
SCHEMBL6432852 0.76 TSHR (0.52) TSHRSMN1; SMN2
SCHEMBL9710305 0.76
SCHEMBL12965171 0.74 SMN1; SMN2 (0.45) TSHRSMN1; SMN2
SCHEMBL11129791 0.74 NOS3 (0.30)
SCHEMBL19818086 0.74 F10 (0.31)
SCHEMBL8767121 0.74 TSHR (0.45) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6933394-B2 Catalyst for synthesizing alkylene carbonate NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2005-08-23 US claimed
EP-1346990-B1 Catalyst for synthesizing alkylene carbonates NAT INST OF ADVANCED IND SCIEN (JP) 2009-06-03 EP disclosed
US-6933394-B2 Catalyst for synthesizing alkylene carbonate NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2005-08-23 US disclosed
US-20040024227-A1 Catalyst for synthesizing alkylene carbonate NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2004-02-05 US disclosed
EP-1346990-A1 Catalyst for synthesizing alkylene carbonates National Institute of Advanced Industrial Science and Technology (JP) 2003-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024227-A1 Catalyst for synthesizing alkylene carbonate SCO2, SMARCC2, CNOT9 TSHR 3708/4885SMN1; SMN2 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.