Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4433744 | 0.95 | PIK3CD (0.53) | PIK3CD | |
| SCHEMBL4182575 | 0.86 | PIK3CD (0.55) | PIK3CD | |
| SCHEMBL10250951 | 0.81 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL4437830 | 0.79 | PIK3CD (0.50) | PIK3CD | |
| SCHEMBL4178301 | 0.79 | PIK3CD (0.61) | PIK3CD | |
| SCHEMBL4174017 | 0.78 | PIK3CD (0.52) | PIK3CD | |
| SCHEMBL4180797 | 0.76 | PIK3CD (0.55) | PIK3CD | |
| SCHEMBL788378 | 0.76 | PIK3CD (0.75) | PIK3CD | |
| SCHEMBL4172242 | 0.75 | PIK3CD (0.49) | PIK3CD | |
| SCHEMBL4437294 | 0.73 | PIK3CD (0.46) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137186-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | Amgen Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008118468-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2008-10-02 | — | — | WO | disclosed |