Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692636 | 1.00 | GRIN2B (0.40) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL4309286 | 1.00 | GRIN2B (0.40) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL3554328 | 0.89 | GRIN2B (0.39) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL2774828 | 0.84 | GRIN2B (0.41) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL1268184 | 0.84 | GRIN2B (0.41) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL199926 | 0.84 | GRIN2B (0.41) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL5578431 | 0.84 | GRIN2B (0.38) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL3000663 | 0.81 | GRIN2B (0.40) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL3000664 | 0.81 | GRIN2B (0.40) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 | |
| SCHEMBL10039817 | 0.81 | GRIN2B (0.40) | GRIN2BGRIN2CJAK3USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043658-A2 | ANTIVIRAL PHOSPHINATE COMPOUNDS | Gilead Sciences, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008005565-A2 | ANTIVIRAL PHOSPHINATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2008-01-10 | — | — | WO | disclosed |
| US-5849893-A | Nucleic acid-binding oligomers possessing C-branching for therapy and diagnostics | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |