SCHEMBL199926

SCHEMBL199926

CC(C)(C)OC(=O)N1CCCC1(O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
USP2 O75604 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CTSK P43235 1/20 0.37
HPGD P15428 1/20 0.36
JAK3 P52333 2/20 0.35
EPHX1 P07099 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PREP P48147 1/20 0.33
EPHX2 P34913 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
USP30 Q70CQ3 1/20 0.32
GPR119 Q8TDV5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2774828 1.00 GRIN2B (0.41) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL1268184 1.00 GRIN2B (0.41) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL4002726 0.93 GRIN2B (0.38) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL2429525 0.90 GRIN2B (0.41) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL3370511 0.90 GRIN2B (0.41) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL4697633 0.87 EPHX1 (0.46) GRIN2BGRIN2CHPGDJAK3EPHX1
SCHEMBL2894589 0.87 MAPK1 (0.40) GRIN2BGRIN2CJAK3USP30GPR119
SCHEMBL4309286 0.84 GRIN2B (0.40) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL4437296 0.84 GRIN2B (0.40) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK
SCHEMBL692636 0.84 GRIN2B (0.40) GRIN2BGRIN2CUSP2SMN1; SMN2CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101695670-A Catalysts for Baylis-Hillman reaction and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2010-04-21 CN claimed
US-12624122-B2 Affinity maturated TAG72 specific single chain antibodies H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2026-05-12 US disclosed
US-12612598-B2 Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy IOVANCE BIOTHERAPEUTICS, INC. (US) 2026-04-28 US disclosed
EP-4720089-A1 COMPOSITIONS AND METHODS FOR IMAGING AND TREATING ENDOMETRIOSIS Endomet Biosciences, Inc. (US) 2026-04-08 EP disclosed
EP-4720088-A1 CONSTRAINED PEPTIDE INHIBITORS OF LRRK2-FADD INTERACTIONS University of Georgia Research Foundation, Inc. (US) 2026-04-08 EP disclosed
EP-4713348-A1 DOUBLY CONSTRAINED PEPTIDES AS ALLOSTERIC INHIBITORS OF LEUCINE RICH REPEAT KINASE 2 University of Georgia Research Foundation, Inc. (US) 2026-03-25 EP disclosed
US-12565520-B2 Chemically-stabilized allosteric modulators of leucine-rich repeat kinase 2 (LRRK2) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2026-03-03 US disclosed
US-20250297033-A1 BISPECIFIC ANTIBODY FOR MEMBRANE CLEARANCE OF TARGET RECEPTORS H LEE MOFFITT CANCER CT & RES (US) 2025-09-25 US disclosed
US-20250242062-A1 ANTI-COX-2 NANOBODIES FOR ENDOSCOPIC VISUALIZATION OF COLORECTAL ADENOMAS VANDERBILT UNIVERSITY 2025-07-31 US disclosed
US-20250195688-A1 Multiplexed Analysis of Materials for Tissue Delivery GEORGIA TECH RESEARCH CORPORATION 2025-06-19 US disclosed
US-5839443-A Method for inhibiting thrombosis in a patient whose blood is subjected to extracorporeal circulation THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-11-24 US disclosed
EP-0765341-A4 TEMPLATE DIRECTED CYCLIZATION SMITHKLINE BEECHAM CORP (US) 1998-09-16 EP disclosed
WO-1998038861-A1 ANTISENSE COMPOUNDS WHICH PREVENT CELL DEATH AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-09-11 WO disclosed
WO-1997042900-A9 METHOD FOR INHIBITING THROMBOSIS IN A PATIENT WHOSE BLOOD IS SUBJECTED TO EXTRACORPOREAL CIRCULATION 1998-03-05 WO disclosed
WO-1998001145-A1 THERAPEUTIC APPLICATIONS OF T-BAM (CD40L) TECHNOLOGY TO TREAT DISEASES INVOLVING SMOOTH MUSCLE CELLS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-01-15 WO disclosed
WO-1997042900-A1 METHOD FOR INHIBITING THROMBOSIS IN A PATIENT WHOSE BLOOD IS SUBJECTED TO EXTRACORPOREAL CIRCULATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1997-11-20 WO disclosed
WO-1997035876-A1 COMPOUNDS WHICH PREVENT NEURONAL CELL DEATH AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1997-10-02 WO disclosed
EP-0765341-A1 TEMPLATE DIRECTED CYCLIZATION SMITHKLINE BEECHAM CORPORATION (US) 1997-04-02 EP disclosed
WO-1995034577-A1 TEMPLATE DIRECTED CYCLIZATION SMITHKLINE BEECHAM CORPORATION (US) 1995-12-21 WO disclosed
EP-0490667-A2 HIV protease inhibitors JAPAN ENERGY CORPORATION (JP) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612598-B2 Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy IL2, ICOS, IL2RA GRIN2B 765/4885GRIN2C 3654/4885USP2 1872/4885
US-12624122-B2 Affinity maturated TAG72 specific single chain antibodies IGLV6-57, CD74, IGSF11 GRIN2B 3325/4885GRIN2C 3970/4885USP2 2478/4885
US-12565520-B2 Chemically-stabilized allosteric modulators of leucine-rich repeat kinase 2 (LRRK2) LRRK2, SNCA, PARK7 GRIN2B 412/4885GRIN2C 364/4885USP2 1108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.