SCHEMBL4437377

SCHEMBL4437377

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C3(c4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc4)CCC(c4ccccc4)CC3)cc2)cc1.Cc1ccc(N(c2ccc(C)cc2)c2ccc(C3(c4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc4)CCCCC3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
OPRM1 P35372 3/20 0.35
SLC6A9 P48067 1/20 0.35
SLC18A3 Q16572 2/20 0.35
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 1/20 0.35
HSD11B1 P28845 2/20 0.34
HSD11B2 P80365 2/20 0.34
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75940 0.95 OPRM1 (0.36) ALDH1A1MEN1KMT2AOPRM1SLC18A3
SCHEMBL4602820 0.91 OPRM1 (0.34) ALDH1A1MEN1KMT2AOPRM1SLC18A3
SCHEMBL10092971 0.86 ESR1 (0.43) ALDH1A1OPRM1ESR1ESR2L3MBTL1
SCHEMBL14732506 0.86 ESR1 (0.43) ALDH1A1OPRM1ESR1ESR2L3MBTL1
SCHEMBL14981798 0.86 ESR1 (0.43) ALDH1A1OPRM1ESR1ESR2L3MBTL1
SCHEMBL24283678 0.86 ESR1 (0.43) ALDH1A1OPRM1ESR1ESR2L3MBTL1
SCHEMBL12223418 0.86 ESR1 (0.43) ALDH1A1OPRM1ESR1ESR2L3MBTL1
SCHEMBL24580403 0.83 ESR1 (0.39) ALDH1A1OPRM1SLC18A3ESR1ESR2
SCHEMBL27271116 0.83 ESR1 (0.39) ALDH1A1OPRM1SLC18A3ESR1ESR2
SCHEMBL24580731 0.83 ESR1 (0.39) ALDH1A1OPRM1SLC18A3ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2115795-A1 FLAT PANEL OLED DEVICE HAVING DEFORMABLE SUBSTRATE Eastman Kodak Company (US) 2009-11-11 EP disclosed
EP-1982320-A1 AN OLED DISPLAY WITH AGING COMPENSATION EASTMAN KODAK COMPANY (US) 2008-10-22 EP disclosed
WO-2008108920-A1 FLAT PANEL OLED DEVICE HAVING DEFORMABLE SUBSTRATE EASTMAN KODAK COMPANY (US) 2008-09-12 WO disclosed
WO-2007053783-A1 AN OLED DISPLAY WITH AGING COMPENSATION EASTMAN KODAK COMPANY (US) 2007-05-10 WO disclosed
WO-2006017189-A1 FLAT PANEL LIGHT EMITTING DEVICES EASTMAN KODAK COMPANY (US) 2006-02-16 WO disclosed
WO-2005020283-A2 WHITE LIGHT-EMITTING DEVICE WITH IMPROVED DOPING EASTMAN KODAK COMPANY (US) 2005-03-03 WO disclosed