Methane

Methane

SCHEMBL4437465

C.Cc1cc(C)c(O)c(C2CCCCC2)c1.Cc1cc(C2CCCC2)c(O)c(C2CCCC2)c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.46
UGT2B17 O75795 2/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.39
TAS1R3 Q7RTX0 3/20 0.39
TAS1R1 Q7RTX1 3/20 0.39
TAS1R2 Q8TE23 3/20 0.39
NR1I2 O75469 1/20 0.39
KDM4B O94953 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
DOHH Q9BU89 1/20 0.39
GAA P10253 2/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL39470 0.98 PSMB5 (0.47) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL11793557 0.96 PSMB5 (0.49) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL10452977 0.96 PSMB5 (0.49) PSMB5UGT2B17KDM4EMAPTMEN1
Ethane SCHEMBL6550192 0.95 PSMB5 (0.47) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL11700915 0.94 PSMB5 (0.46) PSMB5UGT2B17KDM4EMAPTMEN1
Methane SCHEMBL11206867 0.93 KDM4E (0.45) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL10956529 0.91 KDM4E (0.46) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL294290 0.91 KDM4E (0.46) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL2334220 0.91 KDM4E (0.46) PSMB5UGT2B17KDM4EMAPTMEN1
SCHEMBL36429 0.89 KDM4E (0.43) PSMB5UGT2B17KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2118188-A1 POLYMER COMPOSITE EASTMAN KODAK COMPANY (US) 2009-11-18 EP disclosed
WO-2008094500-A1 POLYMER COMPOSITE EASTMAN KODAK COMPANY (US) 2008-08-07 WO disclosed