Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | KDM4B | O94953 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334220 | 1.00 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL10956529 | 1.00 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2APSMB5 | |
| Methane SCHEMBL11206867 | 0.98 | KDM4E (0.45) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL36429 | 0.98 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2APSMB5 | |
| Methane SCHEMBL4437465 | 0.91 | PSMB5 (0.46) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL11793557 | 0.90 | PSMB5 (0.49) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL10452977 | 0.90 | PSMB5 (0.49) | KDM4EMEN1MAPTKMT2APSMB5 | |
| SCHEMBL8990102 | 0.90 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2APSMB5 | |
| Methane SCHEMBL39470 | 0.88 | PSMB5 (0.47) | KDM4EMEN1MAPTKMT2APSMB5 | |
| Ethane SCHEMBL6550192 | 0.88 | PSMB5 (0.47) | KDM4EMEN1MAPTKMT2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725578-B2 | Sterically hindered polymeric amines and their use as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2017-08-08 | — | — | US | disclosed |
| EP-2632914-B1 | NEW STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA SPA (IT) | 2015-12-16 | — | — | EP | disclosed |
| EP-2632914-A1 | NEW STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA S.p.A (IT) | 2013-09-04 | — | — | EP | disclosed |
| US-20130203904-A1 | STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2013-08-08 | — | — | US | disclosed |
| EP-2366732-B1 | Mixtures of sterically hindered amines for polymer stabilisation | 3V SIGMA SPA (IT) | 2013-06-26 | — | — | EP | disclosed |
| US-8404765-B2 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2013-03-26 | — | — | US | disclosed |
| EP-2216364-B9 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA SPA (IT) | 2012-08-15 | — | — | EP | disclosed |
| WO-2012055965-A1 | NEW STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2012-05-03 | — | — | WO | disclosed |
| EP-2216364-B1 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA SPA (IT) | 2012-03-14 | — | — | EP | disclosed |
| EP-2366732-A2 | Mixtures of sterically hindered amines for polymer stabilisation | 3V SIGMA S.p.A (IT) | 2011-09-21 | — | — | EP | disclosed |
| US-20110224336-A1 | MIXTURES OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION | 3V SIGMA S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2010-08-12 | — | — | US | disclosed |
| EP-2216364-A1 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | CBR3, SIGMAR1, NPSR1 | KDM4E 4621/4885MEN1 3952/4885MAPT 3715/4885 |
| US-20130203904-A1 | STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | C1S, AAAS, CBR3 | KDM4E 1977/4885MEN1 4442/4885MAPT 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.