Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447057 | 0.85 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3593210 | 0.84 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3593214 | 0.84 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3593208 | 0.84 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3586898 | 0.79 | ALDH1A1 (0.36) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3593990 | 0.79 | ALDH1A1 (0.36) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3584520 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL13168423 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3584527 | 0.77 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3593940 | 0.77 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |