Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21900333 | 0.88 | SIGMAR1 (0.71) | SIGMAR1HTR1AHRH3SLC6A2HRH1 | |
| T-817 SCHEMBL30574118 | 0.82 | SIGMAR1 (1.00) | SIGMAR1HRH3SLC6A2HRH1CHRM2 | |
| T-817 SCHEMBL27725 | 0.82 | SIGMAR1 (1.00) | SIGMAR1HRH3SLC6A2HRH1CHRM2 | |
| T-817 SCHEMBL47926 | 0.81 | SIGMAR1 (0.98) | SIGMAR1HTR1AHRH3SLC6A2HRH1 | |
| SCHEMBL13505898 | 0.79 | SIGMAR1 (0.68) | SIGMAR1HTR1AHRH3SLC6A2HRH1 | |
| Hydrochloric Acid SCHEMBL5206570 | 0.78 | SIGMAR1 (0.67) | SIGMAR1HTR1AHRH3SLC6A2HRH1 | |
| SCHEMBL48099 | 0.77 | SIGMAR1 (0.83) | SIGMAR1HTR1AHRH3SLC6A2HRH1 | |
| SCHEMBL27025 | 0.77 | SIGMAR1 (0.91) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL47936 | 0.76 | SIGMAR1 (0.81) | SIGMAR1HTR1AHRH3SLC6A2HRH1 | |
| Hydrochloric Acid SCHEMBL47954 | 0.76 | SIGMAR1 (0.89) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348022-B1 | Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2013-01-09 | — | — | EP | disclosed |
| EP-2248809-B1 | Alkyl-3-[2-(benzo[b]thiophen-5-yl)-ethoxy]-propanoates as intermediates in the production of Azetidin-3-ol derivatives | TOYAMA CHEMICAL CO LTD (JP) | 2012-05-09 | — | — | EP | disclosed |
| EP-2210884-B1 | Process for production of 1-(3-(2-(1-benzothiophen-5-yl)-ethoxy)propionic acid or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | disclosed |
| EP-2248809-A1 | Alkyl-3-[2-(benzo[b]thiophen-5-yl)-ethoxy]-propanoates as intermediates in the production of Azetidin-3-ol derivatives | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-11-10 | — | — | EP | disclosed |
| EP-2210884-A2 | Process for production of 1-(3-(2-(1-benzothiophen-5-yl)-ethoxy)propionic acid and 1-(3-(2-(1-benzothiophen-5-yl)-ethoxy)propyl)azetidin-3-ol as well as salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-07-28 | — | — | EP | disclosed |
| EP-1864978-A1 | PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)- ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-12-12 | — | — | EP | disclosed |