Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284709 | 0.82 | KMT2A (0.68) | ALDH1A1HTTNPY5RMEN1KMT2A | |
| SCHEMBL13763409 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTNPY5RMEN1 | |
| SCHEMBL3540913 | 0.80 | KMT2A (0.66) | ALDH1A1HTTNPY5RMEN1KMT2A | |
| SCHEMBL27006685 | 0.79 | KMT2A (0.68) | ALDH1A1HTTNPY5RMEN1KMT2A | |
| SCHEMBL29571128 | 0.79 | KMT2A (0.68) | ALDH1A1HTTNPY5RMEN1KMT2A | |
| SCHEMBL4067677 | 0.78 | KMT2A (0.60) | ALDH1A1HTTNPY5RMEN1KMT2A | |
| SCHEMBL3228138 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL3228129 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL14572299 | 0.77 | RECQL (0.62) | ALDH1A1HTTNPY5RMEN1KMT2A | |
| SCHEMBL14572312 | 0.77 | RECQL (0.62) | ALDH1A1HTTNPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136811-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |