Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.61 |
| ▸ | PGR | P06401 | 5/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.61 |
| ▸ | AR | P10275 | 5/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | APOL1 | O14791 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1348797 | 0.91 | NR3C1 (0.52) | NR3C1PGRNR3C2AR | |
| SCHEMBL1350412 | 0.89 | NR3C1 (0.71) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL1349777 | 0.85 | NR3C1 (0.45) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL1426794 | 0.83 | NR3C1 (0.51) | NR3C1PGRNR3C2AR | |
| SCHEMBL1350367 | 0.80 | NR3C1 (0.58) | NR3C1PGRNR3C2ARHTR6 | |
| SCHEMBL1349075 | 0.79 | NR3C1 (0.58) | NR3C1PGRNR3C2ARSLC6A4 | |
| SCHEMBL8329009 | 0.76 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL8327350 | 0.76 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL29814832 | 0.76 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL1349908 | 0.76 | NR3C1 (0.70) | NR3C1PGRNR3C2ARHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156072-A1 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-12-30 | — | — | WO | disclosed |